(S)-(+)-2-(Dibenzylamino)-3-phenyl-1-propanol

[ Density]:
1.111g/cm3

[ Boiling Point ]:
488ºC at 760mmHg

[ Melting Point ]:
72-74 °C(lit.)

[ Molecular Formula ]:
C₂₃H₂₅NO

[ Molecular Weight ]:
331.45100

[ Flash Point ]:
191.3ºC

[ Exact Mass ]:
331.19400

[ PSA ]:
23.47000

[ LogP ]:
4.29240

[ Vapour Pressure ]:
2.45E-10mmHg at 25°C

[ Index of Refraction ]:
1.613

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922199090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Preparation of Aminoalkyl Chlorohydrin Hydrochlorides: Key Building Blocks for Hydroxyethylamine-Based HIV Protease Inhibitors.

J. Org. Chem. 61 , 3635, (1996)

Enantiomerically pure N,N-dibenzyl-alpha-amino aldehydes reacted with (chloromethyl)lithium, generated in situ from bromochloromethane and lithium metal, to give predominantly erythro aminoalkyl epoxi...

Stereoselective Synthesis of HIV-1 Protease Inhibitor, DMP 323.

J. Org. Chem. 61 , 444, (1996)

DMP 323, a potent HIV-1 protease inhibitor, has been synthesized by an efficient stereoselective process, amenable to large scale preparations. The core C(2) symmetric diol was synthesized by a stereo...

Cyclic HIV protease inhibitors: synthesis, conformational analysis, P2/P2' structure-activity relationship, and molecular recognition of cyclic ureas.

J. Med. Chem. 39 , 3514, (1996)

High-resolution X-ray structures of the complexes of HIV-1 protease (HIV-1PR) with peptidomimetic inhibitors reveal the presence of a structural water molecule which is hydrogen bonded to both the mob...

More Articles