diglyme
Names
[ CAS No. ]:
111-96-6
[ Name ]:
diglyme
[Synonym ]:
diethyleneglycol dimethylether
Bis(2-methoxyethyl) Ether
diethylene glycol dimethyl ether
1-methoxyethoxy-2-methoxyethoxyethane
Dimethylcarbitol
DEG dibenzoate
bis-(2-methoxy ethyl)-ether
MFCD00008503
1-Methoxy-2-(2-methoxyethoxy)ethane
Benzo flex 2-45
diglyme
Bis-(2-benzoyloxy-aethyl)-aether
EINECS 203-924-4
diethyleneglycol dibenzoate
Bis(2-methoxyethyl) ether,AcroSeal,Extra Dry
bis-(2-benzoyloxy-ethyl)-ether
OXY BIS(2-ETHYL BENZOATE)
oxydiethylenedibenzoate
diethylenebenzylbenzoate
Ethane, 2,2'-oxybis[1-methoxy-
2-Methoxyethyl ether
DIGLYCOL DIBENZOATE
Dimethyldiglycol
Diaethylenglykol-dibenzoat
DEGDB
ethane, 1-methoxy-2-(2-methoxyethoxy)-
1O2O2O1
bis(methoxyethyl) ether
2,2-OXYBISETHANOLDIBENZOATE
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
159.8±0.0 °C at 760 mmHg
[ Melting Point ]:
−64 °C(lit.)
[ Molecular Formula ]:
C6H14O3
[ Molecular Weight ]:
134.174
[ Flash Point ]:
70.0±0.0 °C
[ Exact Mass ]:
134.094299
[ PSA ]:
27.69000
[ LogP ]:
-0.80
[ Vapour density ]:
4.6 (vs air)
[ Vapour Pressure ]:
3.2±0.2 mmHg at 25°C
[ Index of Refraction ]:
1.394
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents. May be air or light sensitive.
[ Water Solubility ]:
Miscible
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KN3339000
- CHEMICAL NAME :
- Ether, bis(2-methoxyethyl)
- CAS REGISTRY NUMBER :
- 111-96-6
- BEILSTEIN REFERENCE NO. :
- 1736101
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 20
- MOLECULAR FORMULA :
- C6-H14-O3
- MOLECULAR WEIGHT :
- 134.20
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5400 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6 gm/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 500 mg/kg
- SEX/DURATION :
- female 11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - maternal-fetal exchange
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 13680 mg/kg
- SEX/DURATION :
- male 20 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - other effects on male
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- DOSE :
- 1100 ppm/6H
- SEX/DURATION :
- male 2 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 537 mg/kg
- SEX/DURATION :
- female 11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2500 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system Reproductive - Specific Developmental Abnormalities - urogenital system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2500 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 5 gm/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1250 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1400 mg/kg
- SEX/DURATION :
- female 6-19 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- Dominant lethal test
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 1000 ppm/5D (Continuous)
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB83-138198 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0698 No. of Facilities: 27 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 191 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0698 No. of Facilities: 13 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 207 (estimated) No. of Female Employees: 52 (estimated)
Safety Information
[ Symbol ]:
GHS02, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H226-H360
[ Supplemental HS ]:
May form explosive peroxides.
[ Precautionary Statements ]:
P201-P210-P280-P308 + P313-P370 + P378
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R10;R19;R60;R61
[ Safety Phrases ]:
S53-S45
[ RIDADR ]:
UN 3271 3/PG 3
[ WGK Germany ]:
1
[ RTECS ]:
KN3339000
[ Packaging Group ]:
III
[ Hazard Class ]:
3
[ HS Code ]:
2909199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2909199090
[ Summary ]:
2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
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