2,2'-[ethane-1,2-diylbis(oxy)]bisethyl dinitrate
Names
[ CAS No. ]:
111-22-8
[ Name ]:
2,2'-[ethane-1,2-diylbis(oxy)]bisethyl dinitrate
[Synonym ]:
O,O'-Dinitro-triaethylenglykol
TEGDN
2,2'-(Ethane-1,2-diylbis(oxy))bisethyl dinitrate
EINECS 203-847-6
Ethanol,2,2'-[1,2-ethanediylbis(oxy)]bis-,dinitrate
1,2-bis-(2-nitryloxy-ethoxy)-ethane
2,2'-(1,2-Ethanediylbis(oxy))bisethanol,dinitrate
Triaethylenglykol-dinitrat
1,2-bis-(2-nitrooxy-ethoxy)-ethane
triethyleneglycol-dinitrate
1,2-Bis-(2-nitryloxy-aethoxy)-aethan
Chemical & Physical Properties
[ Density]:
1.344g/cm3
[ Boiling Point ]:
327.2ºC at 760mmHg
[ Molecular Formula ]:
C6H12N2O8
[ Molecular Weight ]:
240.16800
[ Flash Point ]:
146.9ºC
[ Exact Mass ]:
240.05900
[ PSA ]:
128.56000
[ LogP ]:
0.48260
[ Vapour Pressure ]:
0.000392mmHg at 25°C
[ Index of Refraction ]:
1.459
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YE5500000
- CHEMICAL NAME :
- Triethylene glycol, dinitrate
- CAS REGISTRY NUMBER :
- 111-22-8
- BEILSTEIN REFERENCE NO. :
- 1714096
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C6-H12-N2-O8
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - respiratory depression Blood - methemoglobinemia-carboxyhemoglobin Vascular - BP lowering not characterized in autonomic section
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 34,526,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 796 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - irritability Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 34,526,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2520 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - respiratory depression Blood - methemoglobinemia-carboxyhemoglobin Vascular - BP lowering not characterized in autonomic section
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 34,526,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1866 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex)
- REFERENCE :
- ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 12,606,1993
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 945 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - respiratory depression Blood - methemoglobinemia-carboxyhemoglobin Vascular - BP lowering not characterized in autonomic section
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 34,526,1973
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - muscle contraction or spasticity Behavioral - irritability
- REFERENCE :
- ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 12,604,1993
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 34,526,1973 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 106 gm/kg/3W-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 34,526,1973
Safety Information
[ Hazard Class ]:
1.1A
[ HS Code ]:
2920909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2920909090
[ Summary ]:
2920909090 esters of other inorganic acids of non-metals (excluding esters of hydrogen halides) and their salts; their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%