D-Glucose-13C6

Names

[ Name ]:
D-Glucose-13C6

[Synonym ]:
D-Glucose-ul-13C,Dextrose-13C6
2,3,4,5,6-pentahydroxyhexanal
MFCD00037544
D-Glucose-ul-13C,Dextrose-13C6,Labeled Glucose
D-Glucose (U-13C6, 24-25%)

Biological Activity

[Description]:

D-Glucose-13C6 is a tracer used to trace glucose-related synthetic catabolism, is a low-cost alternative with the significant advantage that the sixth isotope of natural glucose has virtually zero natural abundance, which facilitates isotopomer analysis with <1% labeled glucose in the infusate[1][2].

[References]

[1]. Malz F, et al. Synthesis of methyl 4'-O-methyl-beta-D-cellobioside-13C12 from D-glucose-13C6. Part 2: solid-state NMR studies. Carbohydr Res. 2007 Jan 15;342(1):65-70.

[2]. Zhang H, et al. A convenient LC-MS method for assessment of glucose kinetics in vivo with D-[13C6]glucose as a tracer. Clin Chem. 2009 Mar;55(3):527-32.

Chemical & Physical Properties

[ Density]:
1.581g/cm3

[ Melting Point ]:
150-152ºC(lit.)

[ Molecular Formula ]:
₁₃C₆H₁₂O₆

[ Molecular Weight ]:
186.11200

[ Exact Mass ]:
186.08400

[ PSA ]:
110.38000

[ Index of Refraction ]:
1.573

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Articles

A convenient LC-MS method for assessment of glucose kinetics in vivo with D-[13C6]glucose as a tracer.

Clin. Chem. 55 , 527-532, (2009)

The isotope-labeled intravenous glucose tolerance test (IVGTT) combined with computer modeling is widely used to derive parameters related to glucose metabolism in vivo. Most of these methods involve ...

Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress.

BMC Biochem. 6 , 4, (2005)

Heat shock factor (HSF/HSF1) not only is the transcription factor primarily responsible for the transcriptional response of cells to physical and chemical stress but also coregulates other important s...

A convenient gram-scale synthesis of uridine diphospho(13C6)glucose.

Carbohydr. Res. 341 , 1743-1747, (2006)

A simple gram-scale synthesis of uridine diphospho(13C6)glucose is presented from D-(13C6)glucose. The critical step uses a 1H-tetrazole-catalyzed coupling of 2,3,4,6-tetra-O-acetyl-alpha-D-glucopyran...

Related Compounds

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