Methyl hesperidin

Names

[ Name ]:
Methyl hesperidin

[Synonym ]:
Methyl hesperidin
Methyl hesperidine
(2S)-2-[3,4-bis(methyloxy)phenyl]-5-hydroxy-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
(2S)-2-(3,4-Dimethoxyphenyl)-5-hydroxy-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dimethoxyphenyl)-2,3-dihydro-5-hydroxy-, (2S)-

Biological Activity

[Description]:

Methyl-Hesperidin is a vasodilating agent[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

[References]

[1]. Kikuchi K, et al. The potentiation of the coronary dilating and the cardiac action of adenosine or adenine nucleotides by methylhesperidin. Jpn J Pharmacol. 1966 Jun;16(2):224-5.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
900.4±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₉H₃₆O₁₅

[ Molecular Weight ]:
624.587

[ Flash Point ]:
293.0±27.8 °C

[ Exact Mass ]:
624.205444

[ PSA ]:
223.29000

[ LogP ]:
2.55

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.668

[ Storage condition ]:
2-8C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DJ2979400

CHEMICAL NAME :: 4H-1-Benzopyran-4-one, 7-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-gluco pyranosyl) oxy)-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphen yl)-, monomethyl ether

CAS REGISTRY NUMBER :: 11013-97-1

LAST UPDATED :: 199510

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C29-H36-O15

MOLECULAR WEIGHT :: 624.65

WISWESSER LINE NOTATION :: T66 BO EVT&J CR CQ DO1& GO1 IO- BT6OTJ CQ DQ EQ F1O- BT6OTJ CQ DQ EQ F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 53,237S,1957 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 52650 mg/kg

SEX/DURATION :: female 17-22 day(s) after conception lactating female 21 day(s) post-birth

TOXIC EFFECTS :: Reproductive - Effects on Newborn - physical

REFERENCE :: YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 9,1395,1981

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 19500 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 9,1369,1981

Safety Information

[ RIDADR ]:
1479.0

[ Hazard Class ]:
5.1

[ HS Code ]:
29389090

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.