Ascomycin
Names
[ CAS No. ]:
11011-38-4
[ Name ]:
Ascomycin
[Synonym ]:
immunomycin
ascomycin,streptomyces hygroscopicus
(1R,9S,12S,13R,14S,17R,18Z,21S,23S,24R,25S,27R)-17-Ethyl-1,14-dihydroxy-12-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-propen-2-yl}-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatr ;icyclo[22.3.1.0]octacos-18-ene-2,3,10,16-tetrone
aag
ascomycin /immunomycin/fr-900520/fk-520
15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-, (3S,4R,5S,8R,9Z,12S,14S,15R,16S,18R,19R,26aS)-
fk-520
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
868.3±75.0 °C at 760 mmHg
[ Melting Point ]:
156 -161ºC
[ Molecular Formula ]:
C43H69NO12
[ Molecular Weight ]:
792.008
[ Flash Point ]:
478.9±37.1 °C
[ Exact Mass ]:
791.481995
[ PSA ]:
178.36000
[ LogP ]:
3.81
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.546
[ Storage condition ]:
-20°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CI7570000
- CHEMICAL NAME :
- Ascomycin
- CAS REGISTRY NUMBER :
- 11011-38-4
- LAST UPDATED :
- 199212
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAJAAA Journal of Antibiotics, Series A. (Tokyo, Japan) V.6-20, 1953-67. For publisher information, see JANTAJ. Volume(issue)/page/year: 15,231,1962
Safety Information
[ Hazard Codes ]:
Xn
[ Safety Phrases ]:
S36/37
[ RTECS ]:
CI7570000