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12-Epinapelline

Names

[ CAS No. ]:
110064-71-6

[ Name ]:
12-Epinapelline

[Synonym ]:
(1R,2R,4R,5R,7R,8R,10R,13R,17R)-11-Ethyl-13-methyl-6-methylene-11-azahexacyclo[7.7.2.1.0.0.0]nonadecane-4,7,16-triol
12-epinapelline
Epinapelline, 12-

Biological Activity

[Description]:

12-Epinapelline is a diterpene alkaloid isolated from Aconitum baikalense. 12-Epinapelline exhibits Anti-inflammatory activity and stimulates the growth of colonies from fibroblast precursors[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Nesterova YV, et al. Anti-inflammatory activity of diterpene alkaloids from Aconitum baikalense. Bull Exp Biol Med. 2014 Mar;156(5):665-8.

[2]. Nesterova YV, et al. Regeneratory characteristics of complex extract and isolated diterpene alkaloids of Aconitum baikalense. Bull Exp Biol Med. 2012 Feb;152(4):439-43.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
537.8±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C22H33NO3

[ Molecular Weight ]:
359.502

[ Flash Point ]:
284.2±28.8 °C

[ Exact Mass ]:
359.246033

[ PSA ]:
63.93000

[ LogP ]:
0.78

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.638

Related Compounds