1,4-Dibromobutane
Names
[ CAS No. ]:
110-52-1
[ Name ]:
1,4-Dibromobutane
[Synonym ]:
1,4-DIBROMBUTAN
1,4-dibromo-n-butane
EINECS 203-775-5
Butane,1,4-dibromo
1,4-DIBROMOBUTENE
1,4-Dibromobutane
1 4-DIBROMOBUTANE
1,4-Butylene bromide
1,4-bromobutane
1,4 DIBROMBUTANE
MFCD00000261
1,4-dibrombutane
1,4-Dibromo butane
Butane, 1,4-dibromo-
TETRAMETYLENE DIBROMIDE
1,4-Dibrombutan [German]
DIBROMO BUTANE, 1,4-
TETRAMETHYLENE DIBROMIDE
Tetramethylene Bromide
1,4-DIBROMOBUTANE FOR SYNTHESIS
1,4-Dibromobutan
1,4-dibromo-butane
Chemical & Physical Properties
[ Density]:
1.8±0.1 g/cm3
[ Boiling Point ]:
197.0±0.0 °C at 760 mmHg
[ Melting Point ]:
−20 °C(lit.)
[ Molecular Formula ]:
C4H8Br2
[ Molecular Weight ]:
215.914
[ Flash Point ]:
65.2±17.7 °C
[ Exact Mass ]:
213.899261
[ LogP ]:
2.75
[ Vapour Pressure ]:
0.5±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.508
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.
[ Water Solubility ]:
immiscible
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EJ7565000
- CHEMICAL NAME :
- Butane, 1,4-dibromo-
- CAS REGISTRY NUMBER :
- 110-52-1
- BEILSTEIN REFERENCE NO. :
- 1071199
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C4-H8-Br2
- MOLECULAR WEIGHT :
- 215.94
- WISWESSER LINE NOTATION :
- E4E
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 10 umol/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 141,11,1984
Safety Information
[ Symbol ]:
GHS05, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H315-H318-H335-H412
[ Precautionary Statements ]:
P261-P273-P280-P301 + P310-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic
[ Risk Phrases ]:
R25;R36/37/38;R41
[ Safety Phrases ]:
S26-S39-S45-S37/39
[ RIDADR ]:
UN 2810 6.1/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
EJ7565000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
2903399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2903399090
[ Summary ]:
2903399090. brominated,fluorinated or iodinated derivatives of acyclic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
Articles
J. Agric. Food Chem. 63 , 6883-9, (2015)
A series of novel 1,2,3-benzotriazin-4-one derivatives were synthesized by the reaction of 3-bromoalkyl-1,2,3-benzotriazin-4-ones with potassium salt of 2-cyanoimino-4-oxothiazolidine in the presence ...
Synthesis and receptor binding assay of indolin-2-one derivatives as dopamine D4 receptor ligands.Pharmazie 70 , 511-4, (2015)
Five indolin-2-one derivatives bearing piperazinylbutyl side chains attached to the amide nitrogen were synthesized from 2-indolinone. 1-(4-Bromobutyl)-indolin-2-one was reacted with 1-piperazinecarbo...
Metabolism and mutagenicity of source water contaminants 1,3-dichloropropane and 2,2-dichloropropane.Drug Metab. Dispos. 32(1) , 123-31, (2004)
Cytochrome P450-dependent oxidation and glutathione (GSH)-dependent conjugation are the primary routes of metabolism of haloalkanes. Using rat liver microsomes and cytosol, we investigated the metabol...