Murraol

Names

[ Name ]:
Murraol

[Synonym ]:
2H-1-Benzopyran-2-one, 8-[(1E)-3-hydroxy-3-methyl-1-buten-1-yl]-7-methoxy-
7-ethoxy-3,7-dimethyl-2-octen-1-ol
7-Ethoxygeraniol
8-[(1E)-3-Hydroxy-3-methyl-1-buten-1-yl]-7-methoxy-2H-chromen-2-one

Biological Activity

[Description]:

Murraol (CM-c2), a coumarin, can be isolated from the leaves of Madagascar pine cork (Apiaceae). Murraol has cyclooxygenase (COX) and lipoxygenase inhibitory properties and has an inhibitory effect on the growth of cancer cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> 5-Lipoxygenase

Signaling Pathways >> Immunology/Inflammation >> COX

[References]

[1]. Riviere C, et al. Antiproliferative effects of isopentenylated coumarins isolated from Phellolophium madagascariense Baker. Nat Prod Res. 2006 Aug;20(10):909-16.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
466.9±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₆O₄

[ Molecular Weight ]:
260.285

[ Flash Point ]:
176.7±22.2 °C

[ Exact Mass ]:
260.104858

[ PSA ]:
59.67000

[ LogP ]:
2.04

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.604

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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