2-METHYL-N-(1R-NAPHTHALEN-2-YL-ETHYL)-BENZAMIDE

Names

[ CAS No. ]:
1093070-10-0

[ Name ]:
2-METHYL-N-(1R-NAPHTHALEN-2-YL-ETHYL)-BENZAMIDE

[Synonym ]:
2-methyl-N-[2-(2-naphthalenyl)ethyl]benzamide
2-Methyl-N-[(R)-1-(2-naphthyl)ethyl]benzamide

Biological Activity

[Description]:

PLpro-IN-1 (Compound 2) is a SARS-CoV PLpro inhibitor (IC50: 8.7 μM). PLpro-IN-1 can be used for antiviral research[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> SARS-CoV

[Target]

8.7 μM (PLpro)[1]

[References]

[1]. Ratia K, et al. A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication. Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16119-24.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₉NO

[ Molecular Weight ]:
289.37

[ Exact Mass ]:
289.14700

[ PSA ]:
32.59000

[ LogP ]:
4.69550

Related Compounds

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