Ethyl isocyanate
Names
[ CAS No. ]:
109-90-0
[ Name ]:
Ethyl isocyanate
[Synonym ]:
Isocyanatoethane
MFCD00002042
Ethyl isocyanate
1-Isocyanatoethane
ethyl-isocyanate
EINECS 203-717-9
Ethane, isocyanato-
ethane,isocyanato
Ethylisocyanate
isocyanato-ethan
Isocyanic Acid Ethyl Ester
C2H5NCO
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
60.0±3.0 °C at 760 mmHg
[ Melting Point ]:
<-50
[ Molecular Formula ]:
C3H5NO
[ Molecular Weight ]:
71.078
[ Flash Point ]:
-6.7±0.0 °C
[ Exact Mass ]:
71.037117
[ PSA ]:
29.43000
[ LogP ]:
1.36
[ Vapour Pressure ]:
209.5±0.1 mmHg at 25°C
[ Index of Refraction ]:
1.410
[ Water Solubility ]:
Insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NQ8825000
- CHEMICAL NAME :
- Isocyanic acid, ethyl ester
- CAS REGISTRY NUMBER :
- 109-90-0
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C3-H5-N-O
- MOLECULAR WEIGHT :
- 71.09
- WISWESSER LINE NOTATION :
- OCN2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 230 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 240 mg/m3/6H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 50 ug/plate
- REFERENCE :
- ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 44,3017,1980
Safety Information
[ Symbol ]:
GHS02, GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H301-H312 + H332-H315-H319-H334-H335
[ Precautionary Statements ]:
P210-P261-P280-P301 + P310-P305 + P351 + P338-P342 + P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)
[ Hazard Codes ]:
F:Flammable;T:Toxic;
[ Risk Phrases ]:
R11;R20/21;R25;R36/37/38;R42
[ Safety Phrases ]:
S16-S26-S36/37/39-S45
[ RIDADR ]:
UN 2481 3/PG 1
[ WGK Germany ]:
3
[ RTECS ]:
NQ8825000
[ Packaging Group ]:
I
[ Hazard Class ]:
3.1
[ HS Code ]:
29291090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2929109000
[ Summary ]:
2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
J. Colloid. Interface Sci. 456 , 182-9, (2015)
The incorporation of gold nanoparticles in heterojunction solar cells is expected to increase the efficiency due to plasmon effects, but the literature studies are sometimes controversial. In this wor...
Comparison of CYP2D metabolism and hepatotoxicity of the myocardial metabolic agent perhexiline in Sprague-Dawley and Dark Agouti rats.Xenobiotica 45(1) , 3-9, (2014)
1. Perhexiline, a chiral anti-anginal agent, may be useful to develop new cardiovascular therapies, despite its potential hepatotoxicity. 2. This study compared Dark Agouti (DA) and Sprague-Dawley (SD...
Synthesis, Characterization, Antimicrobial and Antitumor Activities of Sucrose Octa(N-ethyl)carbamate.Med. Chem. 12(1) , 22-9, (2016)
Sucrose octa(N-ethyl)carbamate was synthesized directly from sucrose and ethyl isocyanate, and its structure was confirmed by various analytical methods, such as (1)H and (13)C NMR, FTIR, m.p., MS, an...