1-O-Acetyl-6beta-O-Isobutyrylbritannilactone

Names

[ CAS No. ]:
1087072-50-1

[ Name ]:
1-O-Acetyl-6beta-O-Isobutyrylbritannilactone

[Synonym ]:
Propanoic acid, 2-methyl-, (3aR,4R,7aR)-5-[4-(acetyloxy)-1-methylbutyl]-2,3,3a,4,7,7a-hexahydro-6-methyl-3-methylene-2-oxo-4-benzofuranyl ester
(3aR,4R,7aR)-5-(5-Acetoxy-2-pentanyl)-6-methyl-3-methylene-2-oxo-2,3,3a,4,7,7a-hexahydro-1-benzofuran-4-yl 2-methylpropanoate

Biological Activity

[Description]:

1-O-Acetyl-6beta-O-Isobutyrylbritannilactone (compound 5), a sesquiterpene lactone, can be isolated from the flowers of Inula britannica. 1-O-Acetyl-6beta-O-Isobutyrylbritannilactone shows significant cytotoxicity to tumor cells[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Qi J L, et al. Sesquiterpene lactones and their anti-tumor activity from the flowers of Inula britannica. Letters in Drug Design & Discovery, 2008, 5(7): 433-436.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
503.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C21H30O6

[ Molecular Weight ]:
378.459

[ Flash Point ]:
217.4±30.2 °C

[ Exact Mass ]:
378.204254

[ LogP ]:
3.85

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.504

Related Compounds