Gallium tris(2-methyl-4-oxo-4H-pyran-3-olate)

Names

[ Name ]:
Gallium tris(2-methyl-4-oxo-4H-pyran-3-olate)

[Synonym ]:
GALLIUM MALTOLATE
4H-Pyran-4-one, 3-hydroxy-2-methyl-, gallium salt (3:1)
Gallium tris(2-methyl-4-oxo-4H-pyran-3-olate)

Biological Activity

[Description]:

Gallium maltolate (GAM) is an apoptosis inducer with anti-cancer and anti-inflammatory activity. Gallium maltolate (GAM)-induced apoptosis involves the oxidative stress and p53 pathways[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[References]

[1]. Xuesong Wu, et al. Gallium maltolate inhibits human cutaneous T-cell lymphoma tumor development in mice. J Invest Dermatol. 2015 Mar;135(3):877-884.

[2]. F Sampieri, et al. Efficacy of gallium maltolate against Lawsonia intracellularis infection in a rabbit model. J Vet Pharmacol Ther. 2014 Dec;37(6):571-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₅GaO₉

[ Molecular Weight ]:
445.029

[ Exact Mass ]:
443.997192

Safety Information

[ Hazard Codes ]:
Xn

Related Compounds

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