Cyclosporin U

Names

[ Name ]:
Cyclosporin U

[Synonym ]:
1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methyl-4-hexen-1-yl]-1,4,7,10,12,15,25,28-octamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-, (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-
(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methyl-4-hexen-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,25,28-octamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
SMP0V32C6L

Biological Activity

[Description]:

Cyclosporin U (SMP0V32C6L) is an cytostatic agent that plays an important role in preventing rejection of transplanted organs[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Karen M Corbett, et al. Cyclosporin Structure and Permeability: From A to Z and Beyond. J Med Chem. 2021 Sep 23;64(18):13131-13151.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
1306.2±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₆₁H₁₀₉N₁₁O₁₂

[ Molecular Weight ]:
1188.585

[ Flash Point ]:
743.8±34.3 °C

[ Exact Mass ]:
1187.825684

[ LogP ]:
3.67

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.466

Related Compounds

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