3,5-Dimethylaniline

Names

[ CAS No. ]:
108-69-0

[ Name ]:
3,5-Dimethylaniline

[Synonym ]:
3,5-Xylidine
5-Amino-1,3-xylene
3,5-Me2C6H3NH2
3,5-Diemthylaniline
3,5-Me-aniline
3,5-Xylidin
3,5-Xylylamine
3,5-Xylidene
3,5-Dimethy Iani line
5-AMINO-M-XYLENE
m-xylylamine
Benzenamine, 3,5-dimethyl-
3,5-dimethyl-aniline
EINECS 203-607-0
MFCD00007813
3,5-Dimethylaniline
M,M-dimethylaniline

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
218.5±9.0 °C at 760 mmHg

[ Melting Point ]:
7-9 °C

[ Molecular Formula ]:
C₈H₁₁N

[ Molecular Weight ]:
121.180

[ Flash Point ]:
93.3±0.0 °C

[ Exact Mass ]:
121.089149

[ PSA ]:
26.02000

[ LogP ]:
1.86

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.559

[ Water Solubility ]:
<0.1 g/100 mL at 19 ºC

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZE9625000

CHEMICAL NAME :: 3,5-Xylidine

CAS REGISTRY NUMBER :: 108-69-0

LAST UPDATED :: 199709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C8-H11-N

MOLECULAR WEIGHT :: 121.20

WISWESSER LINE NOTATION :: ZR C1 E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 707 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 421 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 1 mg/plate

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11(Suppl 12),1,1988

Safety Information

[ Symbol ]:

GHS06, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301 + H311 + H331-H373-H411

[ Precautionary Statements ]:
P261-P273-P280-P301 + P310-P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T:Toxic;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R23/24/25;R33;R51/53

[ Safety Phrases ]:
S28-S36/37-S45-S61-S28A

[ RIDADR ]:
UN 1711 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
ZE9625000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
2921430090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921430090

[ Summary ]:
HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Epidemiological studies have demonstrated extensive human exposure to the monocyclic aromatic amines, particularly to 3,5-dimethylaniline, and found an association between exposure to these compounds ...

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J. Chromatogr. A. 1216(41) , 6970-3, (2009)

The assessment of human exposure to specific isomers of dimethylanilines (DMA's) is of interest for the evaluation of potential exposure-health outcome relationships. Improved analytical methods will ...