N-Boc-PEG4-bromide

Names

[ Name ]:
N-Boc-PEG4-bromide

[Synonym ]:
13-Bromo-5,8,11-trioxa-2-azatridecanoic Acid 1,1-Dimethylethyl Ester
1-Boc-amino-3,6,9-trioxaundecanyl-11-bromide

Biological Activity

[Description]:

N-Boc-PEG4-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Jan Anderl, et al. Amatoxin-Conjugates with Improved Linkers. US20130259880A1

Chemical & Physical Properties

[ Boiling Point ]:
422.1±35.0°C at 3 mmHg

[ Molecular Formula ]:
C₁₃H₂₆BrNO₅

[ Molecular Weight ]:
356.25300

[ Exact Mass ]:
355.09900

[ PSA ]:
69.51000

[ LogP ]:
2.16020

Related Compounds

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