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Thymoctonan

Names

[ CAS No. ]:
107489-37-2

[ Name ]:
Thymoctonan

[Synonym ]:
THF-gamma2
Thymoctonan
Leu-Glu-Asp-Gly-Pro-Lys-Phe-Leu
C43H67N9O13
thymic humoral factor gamma2

Biological Activity

[Description]:

Thymoctonan (THF-γ2) is the immunomodulatory octapeptide, thymic humoral factor γ2. Thymoctonan has the half-life less than 6 min at 37 °C in blood from human, rat and mouse[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[In Vitro]

Thymoctonan 形成的主要片段在人和大鼠血液中为 Glu-Asp-Gly-Pro-Lys Phe-Leu (2-8)、Asp-Gly Pro-Lys-Phe-Leu (3-8) 和 Glu-Asp Gly-Pro-Rys (2-6)，在小鼠血液中为 2-8 和 2-6[1]。

[References]

[1]. Martignoni M, et al. Degradation of thymic humoral factor γ2 in human, rat and mouse blood: An experimental and theoretical study. Biochim Biophys Acta Proteins Proteom. 2020 Sep;1868(9):140467.  

Chemical & Physical Properties

[ Density]:
1.285g/cm3

[ Boiling Point ]:
1331.1ºC at 760mmHg

[ Molecular Formula ]:
C43H67N9O13

[ Molecular Weight ]:
918.04500

[ Flash Point ]:
758.8ºC

[ Exact Mass ]:
917.48600

[ PSA ]:
358.85000

[ LogP ]:
2.41680

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.564

Related Compounds

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