SM-433
Names
Biological Activity
[Description]:
SM-433, a Smac mimetic, function as inhibitor of inhibitor of apoptosis proteins (IAPs). SM-433 exhibits strong binding affinity XIAP BIR3 protein with an IC50<1 μM. (patent WO2008128171A2)[1].
[Related Catalog]:
[In Vitro]
SM-433 exhibits strong inhibitory activity against MDA-MB -2131 human breast cancer cells and SK-OV-3 ovarian cancer cells (IC50s<10 μM, respectively)[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C32H43N5O4
[ Molecular Weight ]:
561.71
[ Exact Mass ]:
561.33200
[ PSA ]:
117.83000
[ LogP ]:
4.64780
Related Compounds
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