Epsilon-momfluorothrin

Names

[ Name ]:
Epsilon-momfluorothrin

[Synonym ]:
2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl (1R,3R)-3-[(Z)-2-cyanoprop-1-enyl]-2,2-dimethylcyclopropanecarboxylate
[2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl (1R,3R)-3-[(Z)-2-cyano-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate
epsilon-momfluorothrin
2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl (1R)-trans-3-[(Z)-2-cyanoprop-1-enyl]-2,2-dimethylcyclopropanecarboxylate

Biological Activity

[Description]:

Epsilon-momfluorothrin is a type I synthetic pyrethroid insecticide, activates constitutive androstane receptor (CAR), and induces hepatocellular tumors in rats[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

Constitutive androstane receptor[1]

[References]

[1]. Okuda Y, et al. Editor's Highlight: Mode of Action Analysis for Rat Hepatocellular Tumors Produced by the Synthetic Pyrethroid Momfluorothrin: Evidence for Activation of the Constitutive Androstane Receptor and Mitogenicity in Rat Hepatocytes. Toxicol Sci. 2017 Aug 1;158(2):412-430.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₉F₄NO₃

[ Molecular Weight ]:
385.35

[ Exact Mass ]:
385.13000

[ PSA ]:
59.32000

[ LogP ]:
4.17468

[ Storage condition ]:
2-8℃

Related Compounds

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