OLDA

Names

[ Name ]:
OLDA

[Synonym ]:
(9Z)-N-[2-(3,4-Dihydroxyphenyl)ethyl]octadec-9-enamide
(E)-N-[2-(3,4-dihydroxyphenyl)ethyl]octadec-9-enamide
(9Z)-N-[2-(3,4-Dihydroxyphenyl)ethyl]-9-octadecenamide
MFCD05665144
9-Octadecenamide, N-[2-(3,4-dihydroxyphenyl)ethyl]-, (9Z)-

Biological Activity

[Description]:

N-Oleoyldopamine (OLDA) is a product of condensation of oleic acid and dopamine (DA) and an endogenous TRPV1 selective agonist. N-Oleoyldopamine (OLDA) can crosses the blood-brain barrier. N-oleoyl-dopamine protects the heart against ischemia-reperfusion injury via activation of TRPV1[1][2].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

Research Areas >> Cardiovascular Disease

[References]

[1]. Zhong B, et al. N-oleoyldopamine, a novel endogenous capsaicin-like lipid, protects the heart against ischemia-reperfusion injury via activation of TRPV1. Am J Physiol Heart Circ Physiol. 2008;295(2):H728-H735.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
619.5±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₆H₄₃NO₃

[ Molecular Weight ]:
417.625

[ Flash Point ]:
328.5±31.5 °C

[ Exact Mass ]:
417.324280

[ PSA ]:
69.56000

[ LogP ]:
7.77

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.521

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

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