4-Bromo-2-fluorobenzonitrile

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
231.8±20.0 °C at 760 mmHg

[ Melting Point ]:
69-72 °C

[ Molecular Formula ]:
C₇H₃BrFN

[ Molecular Weight ]:
200.008

[ Flash Point ]:
94.0±21.8 °C

[ Exact Mass ]:
198.943283

[ PSA ]:
23.79000

[ LogP ]:
2.26

[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.578

[ Water Solubility ]:
insoluble

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S36/37/39-S26-S22-S36

[ RIDADR ]:
3439

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2926909090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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A series of heteroaryl-pyridine containing inhibitors of Akt are reported. The synthesis and structure-activity relationships are discussed, leading to the discovery of a indazole-pyridine analogue (K...

Application of aryloximes as solid-phase ketone linkers.

Org. Lett. 5(1) , 7-10, (2003)

In both solution and the solid phase, a variety of ketone oxime anions have been treated with 4-substituted-2-fluorobenzonitriles to give the corresponding nucleophilic aromatic substitution aryloxime...

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