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Sitostenone

Names

[ CAS No. ]:
1058-61-3

[ Name ]:
Sitostenone

[Synonym ]:
Sitostenone
Stigmastenone
4-Stigmasten-3-one
Stigmast-4-en-3-one
Sitostene
stigmasta-4-en-3-one

Biological Activity

[Description]:

β-Sitostenone is a sterols that can be isolated from Cochlospermum vitifolium.β-Sitostenone inhibits tyrosinase activity, and has anti-melanogenic and anti-tumor activities[1][2][3].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase

[Target]

Human Endogenous Metabolite


[References]

[1]. Aguilar-Guadarrama AB, et al. Flavonoids, Sterols and Lignans from Cochlospermum vitifolium and Their Relationship with Its Liver Activity. Molecules. 2018 Aug 5;23(8):1952.  

[2]. Chu CW, et al. Biofunctional Constituents from Michelia compressa var. lanyuensis with Anti-Melanogenic Properties. Molecules. 2015 Jul 3;20(7):12166-74.  

[3]. Fan SQ, et al. Sarocladione, a unique 5,10:8,9-diseco-steroid from the deep-sea-derived fungus Sarocladium kiliense. Org Biomol Chem. 2019 Jun 18;17(24):5925-5928.  

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
503.8±17.0 °C at 760 mmHg

[ Molecular Formula ]:
C29H48O

[ Molecular Weight ]:
412.69

[ Flash Point ]:
263.7±11.8 °C

[ Exact Mass ]:
412.370514

[ PSA ]:
17.07000

[ LogP ]:
10.24

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.516

Safety Information

[ Hazard Codes ]:
Xi

Precursor & DownStream

Precursor

DownStream