4-nitro-1H-indole-3-carbaldehyde
Names
[ CAS No. ]:
10553-11-4
[ Name ]:
4-nitro-1H-indole-3-carbaldehyde
[Synonym ]:
4-Nitro-3-formylindol
3-Formyl-4-nitroindole
1H-Indole-3-carboxaldehyde,4-nitro
4-Nitroindol-3-carbaldehyd
4-Nitroindole-3-carboxaldehyde
4-nitro-3-indolecarbaldehyde
4-nitro-indole-3-carbaldehyde
Chemical & Physical Properties
[ Density]:
1.517g/cm3
[ Boiling Point ]:
441.47ºC at 760 mmHg
[ Melting Point ]:
189-193ºC
[ Molecular Formula ]:
C9H6N2O3
[ Molecular Weight ]:
190.15600
[ Flash Point ]:
220.794ºC
[ Exact Mass ]:
190.03800
[ PSA ]:
78.68000
[ LogP ]:
2.41180
[ Vapour Pressure ]:
0mmHg at 25°C
[ Index of Refraction ]:
1.765
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
26-36/37
[ RIDADR ]:
NONH for all modes of transport
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Med. Chem. 54 , 5320, (2011)
Tryptophan catabolism mediated by indoleamine 2,3-dioxygenase (IDO) is an important mechanism of peripheral immune tolerance contributing to tumoral immune resistance. IDO inhibition is thus an active...
Tetrahedron 46 , 6085, (1990)
Molesworth, P., P.; et al.
Aust. J. Chem. 63 , 813, (2010)