1-Ketoaethiopinone

Names

[ Name ]:
1-Ketoaethiopinone

[Synonym ]:
1,2-Naphthalenedione, 7-methyl-3-(1-methylethyl)-8-(4-methyl-1-oxo-4-penten-1-yl)-
3-Isopropyl-7-methyl-8-(4-methyl-4-pentenoyl)-1,2-naphthalenedione

Biological Activity

[Description]:

1-Ketoaethiopinone is an abietane-diterpenoid. 1-Ketoaethiopinone has an α, β-unsaturated carbonyl function. 1-Ketoaethiopinone shows cytotoxic activity against human cancer cell lines MOLT-4 (human lymphoblastic leukemia) and MCF-7 (human breast adenocarcinoma)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Hadavand Mirzaei H, Firuzi O, Chandran J N, et al. Two antiproliferative seco-4, 5-abietane diterpenoids from roots of Salvia ceratophylla L[J]. Phytochemistry letters, 2019.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
467.6±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₂O₃

[ Molecular Weight ]:
310.387

[ Flash Point ]:
200.7±23.9 °C

[ Exact Mass ]:
310.156891

[ LogP ]:
4.67

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.551

Related Compounds

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