Carbamic acid,N-methyl-, ethyl ester
Names
[ CAS No. ]:
105-40-8
[ Name ]:
Carbamic acid,N-methyl-, ethyl ester
[Synonym ]:
N-Methylcarbamic Acid Ethyl Ester
MFCD00041924
ethyl N-methylcarbamate
Ethyl methylcarbamate
EINECS 203-295-6
N-Methylurethane
Chemical & Physical Properties
[ Density]:
0.964g/cm3
[ Boiling Point ]:
172ºC at 760mmHg
[ Molecular Formula ]:
C4H9NO2
[ Molecular Weight ]:
103.12000
[ Flash Point ]:
57.8ºC
[ Exact Mass ]:
103.06300
[ PSA ]:
38.33000
[ LogP ]:
0.75320
[ Vapour Pressure ]:
1.36mmHg at 25°C
[ Index of Refraction ]:
1.418-1.42
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FC2625000
- CHEMICAL NAME :
- Carbamic acid, methyl-, ethyl ester
- CAS REGISTRY NUMBER :
- 105-40-8
- BEILSTEIN REFERENCE NO. :
- 1743375
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C4-H9-N-O2
- MOLECULAR WEIGHT :
- 103.14
- WISWESSER LINE NOTATION :
- 2OVM1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1360 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10 gm/kg/1W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6500 mg/kg/13W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 495 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - body wall Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 495 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 5 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 174,285,1986
Safety Information
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
40
[ Safety Phrases ]:
S36/S37
[ RTECS ]:
FC2625000
[ HS Code ]:
2924199090
Synthetic Route
Customs
[ HS Code ]: 2924199090
[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%