H-Leu-NH2.HCl

Names

[ Name ]:
H-Leu-NH2.HCl

[Synonym ]:
(2S)-2-Amino-4-methylpentanamide, hydrochloride (1:1)
[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]azanium
L-Leucinamide hydrochloride (1:1)
Pentanamide, 2-amino-4-methyl-, (2S)-, hydrochloride (1:1)
ZVYZ1Y1&1 &&L or S Form
(R)-2-Amino-4-Methylvaleramide
EINECS 233-952-2
MFCD00013012
L-Leucinamide Hydrochloride
H-Leu-NH2.HCl

Biological Activity

[Description]:

L-Leucinamide (hydrochloride) is an amino acid derivative with anti-inflammatory properties[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Madan BR, et al. Effect of L-leucinamide hydrochloride on experimental inflammation. Res Commun Chem Pathol Pharmacol. 1987 Dec;58(3):393-6.

Chemical & Physical Properties

[ Density]:
0.98g/cm3

[ Boiling Point ]:
250.9ºC at 760mmHg

[ Melting Point ]:
254-256ºC

[ Molecular Formula ]:
C₆H₁₅ClN₂O

[ Molecular Weight ]:
166.65

[ Flash Point ]:
105.6ºC

[ Exact Mass ]:
166.087296

[ PSA ]:
69.11000

[ LogP ]:
2.04770

[ Vapour Pressure ]:
0.0211mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29241900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

L-Leucinamide hydrogensquarate: spectroscopic and structural elucidation.

Amino Acids 37(4) , 693-701, (2009)

The hydrogensquarate [LeuNH(2)] (HSq) of L-leucinamide has been synthesized and its structure has been determined by single crystal X-ray diffraction. A three dimensional network is formed by hydrogen...

Rotational spectra and computational analysis of two conformers of leucinamide.

J. Phys. Chem. A 115 , 9676-9681, (2011)

Rotational spectra were recorded for two isotopic species of two conformers of the amide derivative of leucine in the range of 10.5-21 GHz and fit to a rigid rotor Hamiltonian. Ab initio calculations ...

Formation of diastereomeric derivatives of 2-arylpropionic acids using L-leucinamide: lack of generality.

J. Chromatogr. A. 431(1) , 228-30, (1988)