Boc-NH-C6-amido-C4-acid

Names

[ CAS No. ]:
10436-21-2

[ Name ]:
Boc-NH-C6-amido-C4-acid

Biological Activity

[Description]:

PROTAC Linker 32 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 32 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

Alkyl/ether


[References]

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Targ. J Med Chem. 2019 Aug 21.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H32N2O5

[ Molecular Weight ]:
344.45

[ Storage condition ]:
2-8°C