Iota-conotoxin RXIA

Names

[ CAS No. ]:
1042682-52-9

[ Name ]:
Iota-conotoxin RXIA

Biological Activity

[Description]:

lota-conotoxin RXIA is an agonist of voltage-gatedsodium channels (Nav1.2, 1.6, 1.7). Iota-conotoxin RXIAcan induce repetitive action potential and seizure in motor axons of frogsafter intracranial injection in mice [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Fiedler B, et al. Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7. Biochem Pharmacol. 2008 Jun 15;75(12):2334-44.  

Chemical & Physical Properties

[ Molecular Formula ]:
C212H310N54O69S8

[ Molecular Weight ]:
4975.57

Related Compounds

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