GCLE
Names
[ CAS No. ]:
104146-10-3
[ Name ]:
GCLE
[Synonym ]:
3-(Chloromethyl)-7-phenylacetylamino cephalosporanic acid p-methoxybenzyl ester
3-Chloromethyl-7-(2-phenylacetamido)-3-cephem-4-carboxylic Acid 4-Methoxybenzyl Ester
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-(chloromethyl)-8-oxo-7-[(2-phenylacetyl)amino]-, (4-methoxyphenyl)methyl ester, (6R,7R)-
GCLE
4-Methoxybenzyl 3-chloromethyl-7-(2-phenylacetamido)-3-cephem-4-carboxylate
EINECS 403-040-0
MFCD00191253
4-Methoxybenzyl (6R,7R)-3-(chloromethyl)-8-oxo-7-[(phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
T46 AN ES GUTJ CMV1R& EO G1G HVO1R DO1 &&(6R,7R)- Form
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
756.6±60.0 °C at 760 mmHg
[ Melting Point ]:
153-155°C
[ Molecular Formula ]:
C24H23ClN2O5S
[ Molecular Weight ]:
486.968
[ Flash Point ]:
411.4±32.9 °C
[ Exact Mass ]:
486.101624
[ PSA ]:
110.24000
[ LogP ]:
1.89
[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C
[ Index of Refraction ]:
1.658
[ Storage condition ]:
-20?C Freezer, Under Inert Atmosphere
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XI0369883
- CHEMICAL NAME :
- 5-Thia-1-azabicyclo(4,2,0)oct-2-ene-2-carboxylic acid, 3-(chloromethyl)-8-oxo- 7-((phenylacetyl)amino)-, (4-methoxyphenyl)methyl ester, (6R-trans)-
- CAS REGISTRY NUMBER :
- 104146-10-3
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C24-H23-Cl-N2-O5-S
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 15(Suppl 1),S94,1996
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 15(Suppl 1),S94,1996
Safety Information
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
R22:Harmful if swallowed. R41:Risk of serious damage to eyes. R43:May cause sensitization by skin contact.
[ Safety Phrases ]:
S26-S36/37/39
[ RTECS ]:
XZ4380000
[ HS Code ]:
2934999090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%