nalorphine hydrobromide
Names
[ CAS No. ]:
1041-90-3
[ Name ]:
nalorphine hydrobromide
[Synonym ]:
N-Allylnormorphine hydrobromide
Nalorphine hydrobromide
C19H21NO3.HBr
Nalorphine bromide
EINECS 213-868-2
Chemical & Physical Properties
[ Boiling Point ]:
493.6ºC at 760mmHg
[ Melting Point ]:
208ºC
[ Molecular Formula ]:
C19H22BrNO3
[ Molecular Weight ]:
392.28700
[ Flash Point ]:
252.3ºC
[ Exact Mass ]:
391.07800
[ PSA ]:
52.93000
[ LogP ]:
2.65030
[ Vapour Pressure ]:
1.46E-10mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QC7705000
- CHEMICAL NAME :
- Morphinan-3,6-alpha-diol, 17-allyl-7,8-didehydro-4,5-alpha-epoxy-, hydrobromide
- CAS REGISTRY NUMBER :
- 1041-90-3
- LAST UPDATED :
- 199512
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C19-H21-N-O3.Br-H
- MOLECULAR WEIGHT :
- 392.33
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 260 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 51,199,1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 921 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 21,668,1969