4-Chlorobenzyl chloride
Names
[ CAS No. ]:
104-83-6
[ Name ]:
4-Chlorobenzyl chloride
[Synonym ]:
Benzene, 1-chloro-4- (chloromethyl)-
4-Chlorobenzyl chloride
EINECS 203-242-7
MFCD00000914
4-Chlorobenzylchloride
Toluene, p,α-dichloro-
Benzene, 1-chloro-4-(chloromethyl)-
α,4-Dichlorotoluene
1-Chloro-4-(chloromethyl)benzene
p-α-Dichlorotoluene
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
223.0±0.0 °C at 760 mmHg
[ Melting Point ]:
27-29 °C(lit.)
[ Molecular Formula ]:
C7H6Cl2
[ Molecular Weight ]:
161.029
[ Flash Point ]:
97.8±0.0 °C
[ Exact Mass ]:
159.984650
[ LogP ]:
3.08
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.547
[ Water Solubility ]:
insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XT0720000
- CHEMICAL NAME :
- Toluene, p,alpha-dichloro-
- CAS REGISTRY NUMBER :
- 104-83-6
- BEILSTEIN REFERENCE NO. :
- 0471558
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C7-H6-Cl2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1075 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 55(5),13,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1156 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 55(5),13,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 5625 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 55(5),13,1990 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10370 mg/kg/9W-I
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Blood - pigmented or nucleated red blood cells Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 55(5),13,1990 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.5 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83213 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 249 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83213 No. of Facilities: 43 (estimated) No. of Industries: 3 No. of Occupations: 21 No. of Employees: 5959 (estimated) No. of Female Employees: 763 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302 + H312 + H332-H317-H411
[ Precautionary Statements ]:
P273-P280
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
C:Corrosive
[ Risk Phrases ]:
R20/21/22;R34;R51/53
[ Safety Phrases ]:
S26-S36/37/39-S45-S29-S61
[ RIDADR ]:
UN 3427 6.1/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
XT0720000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2903999090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2903999090
[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
Exp. Neurol. 64(3) , 632-48, (1979)
Tetrahedron 50 , 4087, (1994)
Synth. Commun. 24 , 2247, (1994)