allosamidin

Names

[ Name ]:
allosamidin

[Synonym ]:
ALLOSAMIDIN
(3aR,4R,5R,6S,6aS)-2-(dimethylamino)-3a,5,6,6a-tetrahydro-4-hydroxy-6-(hydroxymethyl)-4H-cyclopentoxazol-5-yl 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-β-D-allopyranosyl]-2-deoxy-β-D-allopyranoside
(3aR,4R,5R,6S,6aS)-2-dimethylamino-4,5,6,6a-tetrahydro-4-hydroxy-6-hydroxymethyl-3aH-cyclopenta[d][1,3]oxazol-5-yl 2-acetamido-4-O-(2-acetamido-2-deoxy-β-D-allopyranosyl)-2-deoxy-β-D-allopyranoside

Biological Activity

[Description]:

Allosamidin is an insect chitinase inhibitor with an IC50 of 0.35 μM against Bombyx mori chitinase[1].

[Related Catalog]:

Research Areas >> Infection

[Target]

IC50: 0.35 μM (Bombyx mori chitinase)[1]

[In Vivo]

注射 Allosamidin (10 μg/只) 可防止 Bombyx mori 倒数二龄幼虫蜕皮至下一阶段，并导致幼虫死亡[1]。

[References]

[1]. Sakuda S, et al. The structure of allosamidin, a novel insect chitinase inhibitor, produced by Streptomyces sp. Tetrahedron letters, 1986, 27(22): 2475-2478.

Chemical & Physical Properties

[ Density]:
1.78g/cm3

[ Molecular Formula ]:
C₂₅H₄₂N₄O₁₄

[ Molecular Weight ]:
622.61900

[ Exact Mass ]:
622.27000

[ PSA ]:
261.56000

[ Index of Refraction ]:
1.696

Related Compounds

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