NMTCA

Names

[ Name ]:
NMTCA

[Synonym ]:
2-methyl-N-nitrosothiazolidine-4-carboxylic acid

Biological Activity

[Description]:

NMTCA (NMTPRO) is a sulfur-containing N-nitrosamino acid. NMTCA can be used as an indicator of endogenous nitrosation by gas chromatography-thermalenergyanalysis[1][2].

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

[In Vitro]

Smoking is one of the important factors in determining the amounts of NTCA and NMTCA in human urine[3].

[References]

[1]. Ohshima H, et al. Presence in human urine of new sulfur-containing N-nitrosamino acids: N-nitrosothiazolidine 4-carboxylic acid and N-nitroso 2-methylthiazolidine 4-carboxylic acid. IARC Sci Publ. 1984;(57):77-85.

[2]. Tsuda M, et al. Increase in the levels of N-nitrosoproline, N-nitrosothioproline and N-nitroso-2-methylthioproline in human urine by cigarette smoking. Cancer Lett. 1986;30(2):117-124.

[3]. Tsuda M, et al. Effect of cigarette smoking and dietary factors on the amount of N-nitrosothiazolidine 4-carboxylic acid and N-nitroso-2-methyl-thiazolidine 4-carboxylic acid in human urine. IARC Sci Publ. 1987;(84):446-450.

Chemical & Physical Properties

[ Density]:
1.67g/cm3

[ Boiling Point ]:
449.3ºC at 760mmHg

[ Molecular Formula ]:
C₅H₈N₂O₃S

[ Molecular Weight ]:
176.19

[ Flash Point ]:
225.5ºC

[ Exact Mass ]:
176.02600

[ PSA ]:
95.27000

[ LogP ]:
0.45370

[ Vapour Pressure ]:
2.52E-09mmHg at 25°C

[ Index of Refraction ]:
1.688

Related Compounds

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