2-(2-(6-chlorohexyloxy)ethoxy)ethanamine hydrochloride

Names

[ Name ]:
2-(2-(6-chlorohexyloxy)ethoxy)ethanamine hydrochloride

[Synonym ]:
2-{2-[(6-Chlorohexyl)oxy]ethoxy}ethanamine hydrochloride (1:1)
Ethanamine, 2-[2-[(6-chlorohexyl)oxy]ethoxy]-, hydrochloride (1:1)

Biological Activity

[Description]:

2-(2-(6-chlorohexyloxy)ethoxy)ethanamine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₂₃Cl₂NO₂

[ Molecular Weight ]:
260.20112

[ Exact Mass ]:
259.110596

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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