Niclofolan
Names
[ CAS No. ]:
10331-57-4
[ Name ]:
Niclofolan
[Synonym ]:
Bayer 9015
EINECS 233-720-0
ME 3625
Bilevon M
5,5'-dichloro-3,3'-dinitro-2,2'-biphenyldiol
5,5'-dichloro-3,3'-dinitrobiphenyl-2,2'-diol
Niclofolanum [INN-Latin]
Niclofolano [INN-Spanish]
5,5'-Dichloro-3,3'-dinitro-[1,1'-biphenyl]-2,2'-diol
Niclofolan
BAY 9015
Menichlopholan
2,2'-Dihydroxy-3,3'-dinitro-5,5'-dichlor-diphenyl
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
[In Vivo]
[References]
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
424.9±45.0 °C at 760 mmHg
[ Molecular Formula ]:
C12H6Cl2N2O6
[ Molecular Weight ]:
345.092
[ Flash Point ]:
210.8±28.7 °C
[ Exact Mass ]:
343.960297
[ PSA ]:
132.10000
[ LogP ]:
3.97
[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C
[ Index of Refraction ]:
1.706
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DV5075000
- CHEMICAL NAME :
- (1,1'-Biphenyl)-2,2'-diol, 5,5'-dichloro-3,3'-dinitro-
- CAS REGISTRY NUMBER :
- 10331-57-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C12-H6-Cl2-N2-O6
- MOLECULAR WEIGHT :
- 345.10
- WISWESSER LINE NOTATION :
- WNR DQ CG ER BQ CG ENW
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JETOAS Journal Europeen de Toxicologie. (Paris, France) V.1-6, 1968-72. For publisher information, see TOERD9. Volume(issue)/page/year: 4,525,1971
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - domestic
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 17,108,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - wild bird species
- DOSE/DURATION :
- 13 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 21,315,1972 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 10 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- JETOAS Journal Europeen de Toxicologie. (Paris, France) V.1-6, 1968-72. For publisher information, see TOERD9. Volume(issue)/page/year: 4,525,1971
Safety Information
[ Hazard Codes ]:
C
[ HS Code ]:
2907299090
Customs
[ HS Code ]: 2907299090
[ Summary ]:
2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%