D-Erythrose 4-phosphate sodium

Names

[ Name ]:
D-Erythrose 4-phosphate sodium

[Synonym ]:
sodium D-erythrose 4-phosphate
E4P sodium salt
D-Erythrose 4-phosphate sodium salt
4-Phospho-D-erythrose sodium salt

Biological Activity

[Description]:

D-Erythrose 4-phosphate sodium is a phosphate sodium of the simple sugar Erythrose. Erythritol is actually converted into D-Erythrose 4-phosphate that involves three isomerases[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[In Vitro]

Erythritol is a preferential substrate for Brucella. Erythritol is actually converted into D-erythrose-4-phosphate through a set of reactions that involves three isomerases and that allows hexose-monophosphate synthesis and growth by feeding the pentose phosphate shunt[1].

[References]

[1]. Barbier T, et al. Erythritol feeds the pentose phosphate pathway via three new isomerases leading to D-erythrose-4-phosphate in Brucella. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):17815-20.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄H₈NaO₇P

[ Molecular Weight ]:
222.06600

[ Exact Mass ]:
221.99100

[ PSA ]:
136.93000

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2919900090

Customs

[ HS Code ]: 2919900090

[ Summary ]:
2919900090 other phosphoric esters and their salts, including lactophosphates; their halogenated, sulphonated, nitrated or nitrosated derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

Articles

Gas Chromatography-Quadrupole Time-of-Flight Mass Spectrometry-Based Determination of Isotopologue and Tandem Mass Isotopomer Fractions of Primary Metabolites for (13)C-Metabolic Flux Analysis.

Anal. Chem. 87 , 11792-802, (2015)

For the first time an analytical work flow based on accurate mass gas chromatography-quadrupole time-of-flight mass spectrometry (GC-QTOFMS) with chemical ionization for analysis providing a comprehen...

Poisoning pyridoxal 5-phosphate-dependent enzymes: a new strategy to target the malaria parasite Plasmodium falciparum.

PLoS ONE 4(2) , e4406, (2009)

The human malaria parasite Plasmodium falciparum is able to synthesize de novo pyridoxal 5-phosphate (PLP), a crucial cofactor, during erythrocytic schizogony. However, the parasite possesses addition...

Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum.

Biochem. J. 449(1) , 175-87, (2013)

Malaria tropica is a devastating infectious disease caused by Plasmodium falciparum. This parasite synthesizes vitamin B6 de novo via the PLP (pyridoxal 5'-phosphate) synthase enzymatic complex consis...

Related Compounds

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