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GSK2041706A

Names

[ CAS No. ]:
1032824-43-3

[ Name ]:
GSK2041706A

[Synonym ]:
2-{(1S)-1-[1-(3-Isopropyl-1,2,4-oxadiazol-5-yl)-4-piperidinyl]ethoxy}-5-[4-(methylsulfonyl)phenyl]pyrazine
Pyrazine, 2-[(1S)-1-[1-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl]ethoxy]-5-[4-(methylsulfonyl)phenyl]-

Biological Activity

[Description]:

GSK2041706A (GSK706) is a potent G protein-coupled receptor 119 (GPR119) agonist. GSK2041706A can be used for the research of type 2 diabetes[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> GPR119
Research Areas >> Metabolic Disease

[References]

[1]. Matsuoka, R. T. , et al. Development of Large-Scale Routes to Potent GPR119 Receptor Agonists. Organic Process Research & Development (2016):acs.oprd.6b00157.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
646.3±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C23H29N5O4S

[ Molecular Weight ]:
471.573

[ Flash Point ]:
344.7±34.3 °C

[ Exact Mass ]:
471.194031

[ LogP ]:
1.87

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.564

Related Compounds