d(+)fructofuranose 1,6-diphosphate tetra(cyclohexylammonium) salt
Names
[ CAS No. ]:
103213-44-1
[ Name ]:
d(+)fructofuranose 1,6-diphosphate tetra(cyclohexylammonium) salt
[Synonym ]:
D-FRUCTOSE 1,6-DIPHOSPHATE TETRA(CYCLOHEXYLAMMONIUM) SALT
HEXOSE DIPHOSPHATE TETRA(CYCLOHEXYLAMMONIUM) SALT
HARDEN-YOUNG ESTER TETRA(CYCLOHEXYLAMMONIUM) SALT
D-Tagatose-1,6-bisphosphat tetrakis(cyclohexylammonium) Salz
d-fructose 1,6-bisphosphate tetra(cyclohexylammonium) salt
D-FRUCTOSE 1,6-DIPHOSPHATE*TETRA(CYCLOHE XYMAMMONIUM
Chemical & Physical Properties
[ Molecular Formula ]:
C6H26N4O12P2
[ Molecular Weight ]:
408.23800
[ Exact Mass ]:
408.10200
[ PSA ]:
242.22000
[ LogP ]:
0.11440
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
22-24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Life Sci. 90(9-10) , 365-72, (2011)
Fructose-1,6-bisphosphate (FBP) is a glycolytic intermediate with neuroprotective action in various brain injury models. However, the mechanism underlying the neuroprotection of FBP has not been fully...
Fructose-1, 6-bisphosphatase inhibitors for reducing excessive endogenous glucose production in type 2 diabetes.Handbook of Experimental Pharmacology 203 , 279-301, (2011)
Fructose-1,6-bisphosphatase (FBPase), a rate-controlling enzyme of gluconeogenesis, has emerged as an important target for the treatment of type 2 diabetes due to the well-recognized role of excessive...
Inhibition of fructose 1,6-bisphosphatase reduces excessive endogenous glucose production and attenuates hyperglycemia in Zucker diabetic fatty rats.Diabetes 55 , 1747-1754, (2006)
Gluconeogenesis is increased in type 2 diabetes and contributes significantly to fasting and postprandial hyperglycemia. We recently reported the discovery of the first potent and selective inhibitors...