14-Norpseurotin A

Names

[ Name ]:
14-Norpseurotin A

[Synonym ]:
1-Oxa-7-azaspiro[4.4]non-2-ene-4,6-dione, 8-benzoyl-2-[(1S,2S,3Z)-1,2-dihydroxy-3-penten-1-yl]-9-hydroxy-8-methoxy-3-methyl-, (5S,8S,9R)-
14-norpseurotin A
(5S,8S,9R)-8-Benzoyl-2-[(1S,2S,3Z)-1,2-dihydroxy-3-penten-1-yl]-9-hydroxy-8-methoxy-3-methyl-1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione

Biological Activity

[Description]:

14-Norpseurotin is a compound isolated from the culture of Aspergillus fumigatus. 14-Norpseurotin significantly induces neurite outgrowth of rat pheochromocytoma cells (PC12) at a 10.0 microM concentration[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Ge HM, et al. Bioactive alkaloids from endophytic Aspergillus fumigatus. J Nat Prod. 2009;72(4):753-755.

[2]. Bonday ZQ, et al. LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity. ACS Med Chem Lett. 2018;9(7):612-617.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
750.5±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₁H₂₃NO₈

[ Molecular Weight ]:
417.41

[ Flash Point ]:
407.7±32.9 °C

[ Exact Mass ]:
417.142365

[ LogP ]:
2.70

[ Vapour Pressure ]:
0.0±2.6 mmHg at 25°C

[ Index of Refraction ]:
1.634

Related Compounds

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