TIVICICLOVIR

Names

[ Name ]:
TIVICICLOVIR

[Synonym ]:
Tiviciclovir
Tiviciclovir [INN]
9-[3-hydroxy-2-(hydroxymethyl)prop-1-yl]guanine
2-(guanin-9-ylmethyl)propane-1,3-diol
6H-Purin-6-one,2-amino-1,9-dihydro-9-[3-hydroxy-2-(hydroxymethyl)propyl]
AM 188

Biological Activity

[Description]:

Tiviciclovir (AM188) is an antiviral guanosine analog and a hepatitis B virus inhibitor[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> HBV

[References]

[1]. Wang J, et al. Renal excretion mechanisms of the antiviral nucleoside analogue AM 188 in the rat isolated perfused kidney. Clin Exp Pharmacol Physiol. 2004 Jan-Feb;31(1-2):29-34.

Chemical & Physical Properties

[ Density]:
1.78g/cm3

[ Boiling Point ]:
667.1ºC at 760 mmHg

[ Molecular Formula ]:
C₉H₁₃N₅O₃

[ Molecular Weight ]:
239.23100

[ Flash Point ]:
357.3ºC

[ Exact Mass ]:
239.10200

[ PSA ]:
131.04000

[ Vapour Pressure ]:
1.04E-18mmHg at 25°C

[ Index of Refraction ]:
1.784

TIVICICLOVIR

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream