Phenylisocyanate
Controlled Substances
Names
[ CAS No. ]:
103-71-9
[ Name ]:
Phenylisocyanate
[Synonym ]:
Isocyanatobenzene
Fenylisokyanat
isocyanato-benzene
pic
benzeneisocyanate
Additive ti
6-isocyanatobenzene
Phenyl isocyanate
Phenylcarbimide
EINECS 203-137-6
isocyanic acid phenyl ester
phenyl-isocyanate
carbanil
carbanile
mondurp
MFCD00001994
Karbanil
Benzene, isocyanato-
Phenylisocyanate
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
163.0±0.0 °C at 760 mmHg
[ Melting Point ]:
-31.3 °C
[ Molecular Formula ]:
C7H5NO
[ Molecular Weight ]:
119.121
[ Flash Point ]:
55.6±0.0 °C
[ Exact Mass ]:
119.037117
[ PSA ]:
29.43000
[ LogP ]:
2.58
[ Vapour Pressure ]:
2.1±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.523
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents, water, moisture, alcohols, amines, strong bases, strong acids. Protect from air.
[ Water Solubility ]:
decomposes
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DA3675000
- CHEMICAL NAME :
- Benzene, isocyanato-
- CAS REGISTRY NUMBER :
- 103-71-9
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 17
- MOLECULAR FORMULA :
- C7-H5-N-O
- MOLECULAR WEIGHT :
- 119.13
- WISWESSER LINE NOTATION :
- OCNR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - somnolence (general depressed activity)
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 22 mg/m3/4H
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - acute pulmonary edema Lungs, Thorax, or Respiration - cyanosis
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5 mL/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - aggression Lungs, Thorax, or Respiration - dyspnea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - somnolence (general depressed activity) Behavioral - tremor
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 196 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 7130 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7 mg/m3/6H/2W-I
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Lungs, Thorax, or Respiration - bronchiolar constriction Blood - changes in erythrocyte (RBC) count
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 ppb/6H/3W-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Blood - pigmented or nucleated red blood cells Related to Chronic Data - death
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 100 ug/plate
- REFERENCE :
- ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961- Volume(issue)/page/year: 44,3017,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83340 No. of Facilities: 79 (estimated) No. of Industries: 4 No. of Occupations: 7 No. of Employees: 325 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83340 No. of Facilities: 161 (estimated) No. of Industries: 4 No. of Occupations: 5 No. of Employees: 1453 (estimated) No. of Female Employees: 474 (estimated)
Safety Information
[ Symbol ]:
GHS02, GHS05, GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H226-H302-H314-H317-H330-H334
[ Precautionary Statements ]:
P260-P280-P284-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T+:Verytoxic;
[ Risk Phrases ]:
R22;R26;R36/37/38;R42
[ Safety Phrases ]:
S16-S26-S28-S36/37/39-S45-S38-S28A
[ RIDADR ]:
UN 2487 6.1/PG 1
[ WGK Germany ]:
2
[ RTECS ]:
DA3675000
[ Packaging Group ]:
I
[ Hazard Class ]:
6.1
[ HS Code ]:
2929109000
Customs
[ HS Code ]: 2929109000
[ Summary ]:
2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%