Ky1022

Names

[ Name ]:
Ky1022

Biological Activity

[Description]:

KY1022 is a ras destabilizer. KY1022 targets the Wnt/ß-catenin pathway and inhibits development of metastatic colorectal cancer.

[References]

1. Cho YH, Cha PH, Kaduwal S, Park JC, Lee SK, Yoon JS, Shin W, Kim H, Ro EJ, Koo KH, Park KS, Han G, Choi KY. KY1022, a small molecule destabilizing Ras via targeting the Wnt/β-catenin pathway, inhibits development of metastatic colorectal cancer. Oncotarget. 2016 Dec 6;7(49):81727-81740. doi: 10.18632/oncotarget.13172. PubMed PMID: 27835580; PubMed Central PMCID: PMC5348425.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₉N₃OS

[ Molecular Weight ]:
313.42

Related Compounds

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