2-Fluoro-4-isocyanato-1-methylbenzene

Names

[ Name ]:
2-Fluoro-4-isocyanato-1-methylbenzene

[Synonym ]:
Benzene, 2-fluoro-4-isocyanato-1-methyl-
2-Fluoro-4-isocyanato-1-methylbenzene
3-Fluoro-4-methylphenylisocyanate
4-methyl-3-fluorophenyl isocyanate
MFCD00046799

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
206.0±33.0 °C at 760 mmHg

[ Molecular Formula ]:
C₈H₆FNO

[ Molecular Weight ]:
151.138

[ Flash Point ]:
75.1±15.0 °C

[ Exact Mass ]:
151.043335

[ PSA ]:
29.43000

[ LogP ]:
3.21

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.504

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn: Harmful;Xi: Irritant;

[ Risk Phrases ]:
20/21/22-36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2929109000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2929109000

[ Summary ]:
2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Antibacterials. synthesis and structure-activity studies of 3-aryl-2-oxooxazolidines. 4. Multiply-substituted aryl derivatives.

J. Med. Chem. 35(6) , 1156-65, (1992)

The synthesis and structure-activity relationship (SAR) studies of the effect of different polysubstitution patterns in the aromatic ring of 5-(acetamidomethyl)oxazolidinone antibacterials (I) on anti...