P4pal10

Names

[ CAS No. ]:
1021346-05-3

[ Name ]:
P4pal10

Biological Activity

[Description]:

P4pal10 is a PAR4 antagonist. P4pal10 prevents the thrombin-mediated aggregation of mouse platelets in vivo. P4pal10 significantly reduced both the oedema and the granulocyte infiltration induced by Carrageenan (HY-125474)[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Protease-Activated Receptor (PAR)
Research Areas >> Inflammation/Immunology

[Target]

PAR4[1]


[References]

[1]. Houle S, et al. Neutrophils and the kallikrein-kinin system in proteinase-activated receptor 4-mediated inflammation in rodents. Br J Pharmacol. 2005 Nov;146(5):670-8.  

Chemical & Physical Properties

[ Molecular Formula ]:
C65H112N22O13

[ Molecular Weight ]:
1409.72

Related Compounds