CYCLOHEXANAMINIUM ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL HYDROGENDIPHOSPHATE

[ Molecular Formula ]:
C₂₂H₄₁N₇O₁₀P₂

[ Molecular Weight ]:
625.54900

[ Exact Mass ]:
625.23900

[ PSA ]:
304.26000

[ LogP ]:
2.79140

Click to get detail MSDS

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

Adenosine derived from ADP can contribute to inhibition of platelet aggregation in the presence of a P2Y12 antagonist.

Arterioscler. Thromb. Vasc. Biol. 31 , 416-422, (2011)

To investigate whether adenosine diphosphate (ADP)-derived adenosine might inhibit platelet aggregation, especially in the presence of a P2Y₁₂ antagonist, where the effects of ADP at the P2Y₁₂ recepto...

Extracellular Ca(2+) modulates ADP-evoked aggregation through altered agonist degradation: implications for conditions used to study P2Y receptor activation.

Br. J. Haematol. 153 , 83-91, (2011)

ADP is considered a weak platelet agonist due to the limited aggregation responses it induces in vitro at physiological concentrations of extracellular Ca(2+) [(Ca(2+) )(o) ]. Lowering [Ca(2+) ](o) pa...

P2Y receptors in health and disease.

Adv. Pharmacol. 61 , 417-439, (2011)

The purine- and pyrimidine-sensitive P2Y receptors belong to the large group of G-protein-coupled receptors that are the target of approximately one-third of the pharmaceutical drugs used in the clini...

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