CYCLOHEXANAMINIUM ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL HYDROGENDIPHOSPHATE
Names
[ CAS No. ]:
102029-87-8
[ Name ]:
CYCLOHEXANAMINIUM ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL HYDROGENDIPHOSPHATE
[Synonym ]:
Adenosine 5'-diphosphate di(dicyclohexyl)amine salt
Chemical & Physical Properties
[ Molecular Formula ]:
C22H41N7O10P2
[ Molecular Weight ]:
625.54900
[ Exact Mass ]:
625.23900
[ PSA ]:
304.26000
[ LogP ]:
2.79140
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3.0
Articles
Arterioscler. Thromb. Vasc. Biol. 31 , 416-422, (2011)
To investigate whether adenosine diphosphate (ADP)-derived adenosine might inhibit platelet aggregation, especially in the presence of a P2Y₁₂ antagonist, where the effects of ADP at the P2Y₁₂ recepto...
Extracellular Ca(2+) modulates ADP-evoked aggregation through altered agonist degradation: implications for conditions used to study P2Y receptor activation.Br. J. Haematol. 153 , 83-91, (2011)
ADP is considered a weak platelet agonist due to the limited aggregation responses it induces in vitro at physiological concentrations of extracellular Ca(2+) [(Ca(2+) )(o) ]. Lowering [Ca(2+) ](o) pa...
P2Y receptors in health and disease.Adv. Pharmacol. 61 , 417-439, (2011)
The purine- and pyrimidine-sensitive P2Y receptors belong to the large group of G-protein-coupled receptors that are the target of approximately one-third of the pharmaceutical drugs used in the clini...