2-Amino-1,3-bis(carboxylethoxy)propane HCl

Names

[ CAS No. ]:
1020112-73-5

[ Name ]:
2-Amino-1,3-bis(carboxylethoxy)propane HCl

[Synonym ]:
MFCD31692207

Biological Activity

[Description]:

2-Amino-13-bis(carboxylethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₁₇NO₆

[ Molecular Weight ]:
235.23

Related Compounds

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