CP19

Names

[ CAS No. ]:
1018148-68-9

[ Name ]:
CP19

Biological Activity

[Description]:

CP19, a histamine receptor antagonist, is an entry inhibitor against both Ebolavirus (EBOV) and Marburgvirus (MARV) with IC50s of 3.4 μM and 29.5 μM, respectively. CP19 has SI values of 29.4 and 3.4 for EBOV and MARV, respectively. CP19 has antiviral activity[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor
Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Filovirus
Signaling Pathways >> GPCR/G Protein >> Histamine Receptor

[Target]

Histamine Receptor


[References]

[1]. Yinyi Gao, et al. Development of coumarine derivatives as potent anti-filovirus entry inhibitors targeting viral glycoprotein. Eur J Med Chem. 2020 Oct 15;204:112595.  

Chemical & Physical Properties

[ Molecular Formula ]:
C26H30N2O5

[ Molecular Weight ]:
450.53

Related Compounds

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