Mitomycin D
Names
[ CAS No. ]:
10169-34-3
[ Name ]:
Mitomycin D
[Synonym ]:
(1aS,8R,8aR,8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-1,5-dimethylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione
Chemical & Physical Properties
[ Density]:
1.64g/cm3
[ Boiling Point ]:
601.7ºC at 760mmHg
[ Molecular Formula ]:
C15H18N4O5
[ Molecular Weight ]:
334.32700
[ Flash Point ]:
317.7ºC
[ Exact Mass ]:
334.12800
[ PSA ]:
138.96000
[ Vapour Pressure ]:
5.47E-17mmHg at 25°C
[ Index of Refraction ]:
1.723
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CN0726000
- CAS REGISTRY NUMBER :
- 10169-34-3
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C15-H18-N4-O5
- MOLECULAR WEIGHT :
- 334.37
- WISWESSER LINE NOTATION :
- T D3 B556 BN EN JV MVTTT&J E1 GQ H1OVZ KZ L1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 430 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 36,1461,1993
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAJAAA Journal of Antibiotics, Series A. (Tokyo, Japan) V.6-20, 1953-67. For publisher information, see JANTAJ. Volume(issue)/page/year: 20,72,1967