PETCM

Names

[ Name ]:
PETCM

[Synonym ]:
Apoptosis Activator I
PETCM

Biological Activity

[Description]:

PETCM is an activator of caspase-3. PETCM can induces cell apoptosis and stimulate apoptosome formation in HeLa cell cytosols[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Signaling Pathways >> Apoptosis >> Caspase

[Target]

Caspase 3

[References]

[1]. [1].Jiang X, Kim HE, Shu H, et al. Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway. Science, 2003, 299(5604): 223-226.

Chemical & Physical Properties

[ Density]:
1.465g/cm3

[ Boiling Point ]:
342.2ºC at 760mmHg

[ Molecular Formula ]:
C₈H₈Cl₃NO

[ Molecular Weight ]:
240.51400

[ Flash Point ]:
160.8ºC

[ Exact Mass ]:
238.96700

[ PSA ]:
33.12000

[ LogP ]:
2.35520

[ Vapour Pressure ]:
2.94E-05mmHg at 25°C

[ Index of Refraction ]:
1.579

Safety Information

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
22

[ Safety Phrases ]:
36

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%