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7-Oxotridecanedioic acid

Names

[ CAS No. ]:
101171-43-1

[ Name ]:
7-Oxotridecanedioic acid

[Synonym ]:
7-oxo-trideca-2(Z),11(Z)-diene dinitrile
7-oxo-trideca-2,11-dienedinitrile
7-oxo-tridecane-1,13-dioic acid
7-oxo-tridecanedioic acid
(2Z,11Z)-7-oxotrideca-2,11-dienedinitrile
7-Oxo-tridecandisaeure
(Z,Z)-tridecan-2,11-diene-7-one-1,13-dinitrile
2,11-Tridecadienedinitrile,7-oxo-,(2Z,11Z)

Biological Activity

[Description]:

7-Oxotridecanedioic acid is a biodegradable cationic lipid intermediate compound for lipid nanoparticles formation. 7-Oxotridecanedioic acid can be incorporated into a lipid particle for delivering active agents[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

These cationic lipids can be incorporated into a lipid particle for delivering an active agent, such as a nucleic acid. 7-Oxotridecanedioic acid is extracted from patent US20150005363, intermediate 12[1].

[References]

[1]. Martin A Maier, et al. Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics. Mol Ther. 2013 Aug;21(8):1570-8.

[2]. Steven M Ansell, et al. Branched Alkyl And Cycloalkyl Terminated Biodegradable Lipids For The Delivery Of Active Agents. Patent US20150005363A1

Chemical & Physical Properties

[ Density]:
1.125g/cm3

[ Boiling Point ]:
490.2ºC at 760 mmHg

[ Molecular Formula ]:
C13H22O5

[ Molecular Weight ]:
258.31100

[ Flash Point ]:
264.4ºC

[ Exact Mass ]:
258.14700

[ PSA ]:
91.67000

[ LogP ]:
2.62570

[ Vapour Pressure ]:
5.96E-11mmHg at 25°C

[ Index of Refraction ]:
1.482

Safety Information

[ HS Code ]:
2918300090

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%


Related Compounds

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